I have been using QB64 for quite a while.  I recently purchased a new computer using Windows 10 Home Version 1909 (OS Build 18363.900).   After unpacking the zip file for QB64 Version 1.4, moving the QB64 directory to c:\%homepath%, (e.g. c:\users\USERID) and launching the QB64.exe application, I got the following error message in a black window:

UNEXPECTED INTERNAL COMPILER ERROR!
Caused by (or after): 
Line 0:
Press any key to continue

RhoSigma also reported on this in the forum regarding QB64x32 on December 22, 2018, 11:45:56 AM

Today, I discovered that I could place the QB64 directory in other places and the application launches normally.  An older version (V.954) did not have this problem.

The following locations worked:
c:\%homepath%\MyDirectory
c:\MyDirectory

The following locations did not work:
c:\%homepath%
c:\Program Files (x86)

I am new to this forum.  Sorry, I could not reply to the original post.  Perhaps it is locked.